SCHEMBL1363432

SCHEMBL1363432

CC(C)CN1C(=O)N(C)C(=O)C1(C)S

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 2/20 0.33
KMT2A Q03164 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE7A Q13946 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4620469 1.00 PIK3CD (0.33) PIK3CDKMT2APDE4BPDE7AALDH1A1
SCHEMBL1364185 0.80 RAB9A (0.33)
SCHEMBL1363516 0.79 PIK3CD (0.31) PIK3CDKMT2APDE4BPDE7A
SCHEMBL1364168 0.79 F2 (0.32)
SCHEMBL1362903 0.77
SCHEMBL1363355 0.74 GAA (0.36) KMT2APDE4B
SCHEMBL1362316 0.71 LMNA (0.30)
SCHEMBL1364225 0.69 PIK3CD (0.34) PIK3CDKMT2A
SCHEMBL4621192 0.69 PIK3CD (0.34) PIK3CDKMT2A
SCHEMBL1363456 0.69 LMNA (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8066977-B2 Agent for permanent hair waving containing heterocyclic mercapto compound SHOWA DENKO K.K. (JP) 2011-11-29 US disclosed
EP-1883454-B1 AGENT FOR PERMANENT HAIR WAVING CONTAINING HETEROCYCLIC MERCAPTO COMPOUND SHOWA DENKO KK (JP) 2009-11-04 EP disclosed
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound SHOWA DENKO K.K. (JP) 2009-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208439-A1 Agent for Permanent Hair Waving Containing Heterocyclic Mercapto Compound NSD3, WNT3, MSRB3 PIK3CD 4863/4885KMT2A 1314/4885PDE4B 4539/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.