SCHEMBL13634336

SCHEMBL13634336

CCc1csc(N2CCC(F)(F)CC2)n1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OGA O60502 2/20 0.46
CTSB P07858 1/20 0.42
CTSS P25774 1/20 0.42
CTSK P43235 1/20 0.42
F2RL3 Q96RI0 2/20 0.38
MAPT P10636 1/20 0.36
HRH3 Q9Y5N1 2/20 0.36
LMNA P02545 2/20 0.35
MEN1 O00255 1/20 0.35
MAPK1 P28482 1/20 0.35
KMT2A Q03164 1/20 0.35
PTPN1 P18031 1/20 0.34
PTPN6 P29350 1/20 0.34
CDC25A P30304 1/20 0.34
DNM1L O00429 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15356491 0.84 HRH3 (0.46) OGACTSBCTSSCTSKF2RL3
SCHEMBL13634206 0.84 OGA (0.43) OGACTSBCTSSCTSKMAPT
SCHEMBL13634338 0.82 OGA (0.41) OGACTSBCTSSCTSKHRH3
SCHEMBL10279631 0.82 OGA (0.48) OGACTSBCTSSCTSKMAPT
SCHEMBL13612870 0.79 ALDH1A1 (0.50) OGACTSBCTSSCTSKMAPT
SCHEMBL11919170 0.78 AOC3 (0.49) OGACTSBCTSSCTSKMAPT
SCHEMBL18674655 0.78 LMNA (0.58) OGAMAPTLMNAMEN1MAPK1
Hydrochloric Acid SCHEMBL17541662 0.76 AOC3 (0.48) OGACTSBCTSSCTSKMAPT
SCHEMBL26618117 0.76 SMN1; SMN2 (0.39) MAPTHRH3LMNAMEN1MAPK1
SCHEMBL22334855 0.75 HRH4 (0.46) OGACTSBCTSSCTSKMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304547-B2 Azolecarboxamide compound or salt thereof ASTELLAS PHARMA INC. (JP) 2012-11-06 US disclosed