Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | DNM1L | O00429 | 8/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634206 | 0.85 | OGA (0.43) | OGACTSBCTSSCTSKDNM1L | |
| SCHEMBL13634336 | 0.82 | OGA (0.46) | OGACTSBCTSSCTSKDNM1L | |
| SCHEMBL10279631 | 0.80 | OGA (0.48) | OGACTSBCTSSCTSKDNM1L | |
| SCHEMBL15888627 | 0.75 | OGA (0.48) | OGAACACBSMN1; SMN2HSD17B10 | |
| SCHEMBL13634345 | 0.74 | PTGER1 (0.45) | OGASMN1; SMN2 | |
| SCHEMBL13162286 | 0.73 | HRH3 (0.32) | HRH3ACACBARTP53ALOX15 | |
| SCHEMBL18674677 | 0.72 | OGA (0.41) | OGACTSBCTSSCTSKAR | |
| SCHEMBL13634188 | 0.72 | DNM1L (0.49) | OGACTSBCTSSCTSKDNM1L | |
| SCHEMBL13634369 | 0.72 | LRRK2 (0.33) | — | |
| SCHEMBL13612870 | 0.71 | ALDH1A1 (0.50) | OGACTSBCTSSCTSKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |