Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DNM1L | O00429 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634338 | 0.85 | OGA (0.41) | OGACTSBCTSSCTSKHRH3 | |
| SCHEMBL13634336 | 0.84 | OGA (0.46) | OGACTSBCTSSCTSKHRH3 | |
| SCHEMBL17115633 | 0.80 | LMNA (0.36) | HRH3MAPTLMNAMEN1MAPK1 | |
| SCHEMBL10279631 | 0.77 | OGA (0.48) | OGACTSBCTSSCTSKMAPT | |
| SCHEMBL15709772 | 0.77 | ALDH1A1 (0.43) | HRH3MAPTMEN1KMT2ANPC1 | |
| SCHEMBL13612870 | 0.75 | ALDH1A1 (0.50) | OGACTSBCTSSCTSKMAPT | |
| SCHEMBL18674655 | 0.73 | LMNA (0.58) | OGAMAPTLMNAMEN1MAPK1 | |
| SCHEMBL11919170 | 0.73 | AOC3 (0.49) | OGACTSBCTSSCTSKMAPT | |
| SCHEMBL13634334 | 0.73 | DNM1L (0.42) | OGACTSBCTSSCTSKHRH3 | |
| SCHEMBL18674677 | 0.73 | OGA (0.41) | OGACTSBCTSSCTSKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |