Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.45 |
| ▸ | OGA | O60502 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 6/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162312 | 0.86 | KDM4E (0.44) | PTGER1OGALDHAKDM4EALDH1A1 | |
| SCHEMBL13162578 | 0.83 | OGA (0.46) | PTGER1OGALDHACRBNKDM4E | |
| SCHEMBL15888627 | 0.82 | OGA (0.48) | OGACRBNKDM4EALDH1A1GAA | |
| SCHEMBL3435648 | 0.81 | PTGER1 (0.56) | PTGER1OGALDHAKDM4EALDH1A1 | |
| SCHEMBL3435678 | 0.79 | PTGER1 (0.59) | PTGER1OGALDHAKDM4EALDH1A1 | |
| SCHEMBL13634338 | 0.74 | OGA (0.41) | OGASMN1; SMN2 | |
| SCHEMBL3435714 | 0.74 | PTGER1 (0.46) | PTGER1OGALDHAKDM4EALDH1A1 | |
| SCHEMBL3435749 | 0.74 | PTGER1 (0.46) | PTGER1OGALDHAKDM4EALDH1A1 | |
| SCHEMBL13634273 | 0.73 | RIPK1 (0.34) | — | |
| SCHEMBL2770015 | 0.73 | DNM1L (0.46) | PTGER1OGALDHAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |