Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 9/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13163111 | 0.85 | EPHX2 (0.47) | EPHX2RET | |
| SCHEMBL15888649 | 0.85 | NAAA (0.43) | EPHX2NAAACYP2C9KDM4EACACB | |
| SCHEMBL13163108 | 0.82 | EPHX2 (0.42) | EPHX2CYP2C9KDM4EACACB | |
| SCHEMBL13634347 | 0.79 | KDM5A (0.44) | EPHX2ACACBRET | |
| SCHEMBL13634227 | 0.79 | DPP4 (0.44) | ACACB | |
| SCHEMBL13634319 | 0.78 | NAAA (0.48) | EPHX2NAAACYP2C9KDM4ECHRM2 | |
| SCHEMBL13634229 | 0.77 | HRH3 (0.40) | — | |
| SCHEMBL13634225 | 0.76 | EPHX2 (0.38) | EPHX2CYP2C9KDM4EACACB | |
| SCHEMBL13162320 | 0.76 | NAAA (0.43) | EPHX2NAAACYP2C9KDM4ECHRM2 | |
| SCHEMBL5266581 | 0.75 | EPHX2 (0.60) | EPHX2NAAACYP2C9CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |