Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.45 |
| ▸ | RET | P07949 | 3/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162802 | 0.94 | RET (0.41) | PDE3BPDE3APDE10ARETACACB | |
| SCHEMBL13638796 | 0.87 | CYP11B2 (0.32) | ACACBCYP11B2 | |
| SCHEMBL13162326 | 0.81 | OGA (0.34) | EPHX2 | |
| SCHEMBL13638964 | 0.80 | AOC3 (0.33) | PDE10A | |
| SCHEMBL13634302 | 0.80 | PDE3B (0.47) | PDE3BPDE3APDE10ARETACACB | |
| SCHEMBL13162320 | 0.80 | NAAA (0.43) | RETEPHX2 | |
| SCHEMBL13162784 | 0.78 | — | — | |
| SCHEMBL13638745 | 0.77 | PIN1 (0.30) | — | |
| SCHEMBL13634347 | 0.77 | KDM5A (0.44) | PDE3BPDE3APDE10ARETACACB | |
| SCHEMBL13162794 | 0.76 | CHRM4 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |