Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638750 | 0.89 | KMT2A (0.56) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13634407 | 0.89 | KMT2A (0.52) | LMNAALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL13634242 | 0.87 | SMN1; SMN2 (0.50) | LMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL13634236 | 0.85 | MEN1 (0.61) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13162553 | 0.81 | ALDH1A1 (0.57) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL377882 | 0.81 | SIGMAR1 (0.54) | ALDH1A1KMT2APOLBSIGMAR1 | |
| SCHEMBL13634408 | 0.78 | GRM2 (0.43) | LMNAALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL13162599 | 0.78 | KMT2A (0.68) | LMNAALDH1A1SMN1; SMN2KMT2ATSHR | |
| SCHEMBL15888559 | 0.78 | HTR4 (0.51) | ALDH1A1SMN1; SMN2KMT2APOLBSIGMAR1 | |
| SCHEMBL13161894 | 0.77 | MCHR1 (0.46) | SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |