Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634241 | 0.89 | LMNA (0.48) | KMT2ALMNASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL13162599 | 0.89 | KMT2A (0.68) | KMT2AKDM4ELMNANPC1RAB9A | |
| SCHEMBL13162383 | 0.87 | KMT2A (0.53) | KMT2AKDM4ELMNA | |
| SCHEMBL13634408 | 0.84 | GRM2 (0.43) | KMT2AKDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL13634373 | 0.84 | KMT2A (0.57) | KMT2ALMNASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL13634176 | 0.81 | NOS1 (0.50) | AOC3LMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2774659 | 0.81 | ALDH1A1 (0.59) | KMT2AKDM4EAOC3LMNANPC1 | |
| SCHEMBL13634358 | 0.81 | CNR2 (0.47) | KDM4ELMNAMAPTTSHR | |
| SCHEMBL10272436 | 0.80 | KMT2A (0.77) | KMT2AKDM4ELMNANPC1RAB9A | |
| SCHEMBL145235 | 0.80 | PARP1 (0.49) | AOC3LMNASMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |