Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 11/20 | 0.52 |
| ▸ | DRD2 | P14416 | 9/20 | 0.52 |
| ▸ | DRD3 | P35462 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771960 | 0.83 | CCR5 (0.52) | DRD4DRD2DRD3KDM4ECCR5 | |
| SCHEMBL1546406 | 0.81 | MEN1 (0.56) | DRD4DRD2DRD3CCR5CYP1A2 | |
| SCHEMBL13634377 | 0.79 | DRD2 (0.50) | DRD4DRD2DRD3CCR5HDAC3 | |
| SCHEMBL13634184 | 0.77 | ALDH1A1 (0.56) | DRD4DRD2DRD3KDM4EMAPK1 | |
| SCHEMBL2403289 | 0.77 | KDM4E (0.55) | KDM4EHSD17B10HDAC3HDAC1HDAC2 | |
| SCHEMBL1546767 | 0.77 | DRD2 (0.50) | DRD2KDM4ECCR5HDAC3HDAC4 | |
| SCHEMBL13163940 | 0.76 | KDM4E (0.54) | DRD4DRD2DRD3KDM4EMAPK1 | |
| SCHEMBL8681974 | 0.76 | MEN1 (0.62) | KDM4EMAPK1HSD17B10 | |
| SCHEMBL13634249 | 0.75 | KDM4E (0.58) | KDM4EMAPK1HSD17B10ACHE | |
| SCHEMBL15712821 | 0.74 | ALDH1A1 (0.53) | KDM4EHSD17B10HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |