Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162822 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL15888610 | 0.90 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL13634236 | 0.88 | MEN1 (0.61) | SMN1; SMN2MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL13270661 | 0.86 | KMT2A (0.59) | SMN1; SMN2MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL13634242 | 0.86 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAALDH1A1MAOB | |
| SCHEMBL13270618 | 0.81 | HTR1A (0.54) | SMN1; SMN2MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL2771188 | 0.79 | SIRT6 (0.53) | SMN1; SMN2MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL13634373 | 0.78 | KMT2A (0.57) | SMN1; SMN2MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL13162819 | 0.76 | KMT2A (0.63) | SMN1; SMN2MEN1KMT2ALMNACYP2C19 | |
| SCHEMBL28677732 | 0.76 | SMN1; SMN2 (0.63) | SMN1; SMN2MEN1KMT2ALMNACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |