Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | BCL3 | P20749 | 1/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634241 | 0.87 | LMNA (0.48) | SMN1; SMN2LMNAALDH1A1TSHR | |
| SCHEMBL13634405 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAALDH1A1MAOB | |
| SCHEMBL13163120 | 0.85 | CCR2 (0.41) | — | |
| SCHEMBL13638750 | 0.85 | KMT2A (0.56) | SMN1; SMN2LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL377882 | 0.79 | SIGMAR1 (0.54) | ALDH1A1KDM4E | |
| SCHEMBL13162553 | 0.78 | ALDH1A1 (0.57) | SMN1; SMN2LMNAALDH1A1TSHRKDM4E | |
| SCHEMBL13164017 | 0.76 | KMT2A (0.50) | LMNAALDH1A1TSHR | |
| SCHEMBL26757979 | 0.76 | SMN1; SMN2 (0.78) | SMN1; SMN2LMNAALDH1A1KDM4EMAOB | |
| SCHEMBL13634407 | 0.76 | KMT2A (0.52) | SMN1; SMN2LMNAALDH1A1TSHRKDM4E | |
| SCHEMBL13161894 | 0.75 | MCHR1 (0.46) | SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |