Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13270661 | 0.90 | KMT2A (0.59) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL13634373 | 0.90 | KMT2A (0.57) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL13634405 | 0.88 | SMN1; SMN2 (0.59) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL13634241 | 0.85 | LMNA (0.48) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL2771188 | 0.83 | SIRT6 (0.53) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL13270618 | 0.82 | HTR1A (0.54) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL13162819 | 0.80 | KMT2A (0.63) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL13634404 | 0.79 | LMNA (0.46) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL15888610 | 0.78 | SMN1; SMN2 (0.46) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 | |
| SCHEMBL13162822 | 0.78 | SMN1; SMN2 (0.46) | MEN1KMT2ALMNACYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |