Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12752565 | 0.86 | CYP2A6 (0.41) | CYP2A6DAOSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2607619 | 0.81 | CA2 (0.46) | CYP2A6DAOSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17858547 | 0.78 | CYP2A6 (0.43) | CYP2A6DAOSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL594781 | 0.73 | CYP2A6 (0.46) | CYP2A6DAOSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26200143 | 0.72 | DAO (0.40) | CYP2A6DAOSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6547270 | 0.69 | ALDH1A1 (0.41) | CYP2A6 | |
| SCHEMBL2610672 | 0.69 | CYP2A6 (0.50) | CYP2A6DAOSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1716589 | 0.69 | ADORA2A (0.37) | CYP2A6ADORA2AADORA1HDAC4 | |
| SCHEMBL4403501 | 0.69 | DAO (0.42) | CYP2A6DAOSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15582374 | 0.68 | KCNJ11 (0.42) | CYP2A6ADORA2AADORA1HDAC4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | TEIJIN PHARMA LIMITED (JP) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291945-A1 | CYSTEINE PROTEASE INHIBITORS | CTSE, SPINT2, CTSF | CYP2A6 1382/4885DAO 1538/4885SLC6A2 2542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.