Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 5/20 | 0.44 |
| ▸ | KIT | P10721 | 5/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | BLK | P51451 | 1/20 | 0.41 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.41 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 6/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638941 | 0.90 | MAP3K7 (0.43) | SCDABL1KITMAP3K7FGFR1 | |
| SCHEMBL13634698 | 0.90 | MAP3K7 (0.47) | SCDABL1KITMAP3K7FGFR1 | |
| SCHEMBL13634648 | 0.89 | MAP3K7 (0.51) | MAP3K7FGFR1GPR6EGFRLRRK2 | |
| SCHEMBL13634863 | 0.89 | MAP3K7 (0.48) | SCDMAP3K7FGFR1GPR6IRAK4 | |
| SCHEMBL13638934 | 0.89 | SCD (0.49) | SCDABL1KITGPR6 | |
| SCHEMBL13162054 | 0.89 | SCD (0.50) | SCDGPR6 | |
| SCHEMBL13634736 | 0.87 | MAP3K7 (0.40) | SCDMAP3K7FGFR1GPR6IRAK4 | |
| SCHEMBL13634882 | 0.81 | MAP3K7 (0.39) | SCDMAP3K7GPR6LRRK2 | |
| SCHEMBL13634880 | 0.79 | RAB9A (0.40) | SCDMAP3K7 | |
| SCHEMBL13634547 | 0.79 | MAP3K7 (0.39) | SCDMAP3K7GPR6LRRK2IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |