Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 11/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.37 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634828 | 0.92 | RAB9A (0.41) | RAB9ANPC1MAPK1MEN1KMT2A | |
| SCHEMBL13634863 | 0.90 | MAP3K7 (0.48) | SCDMAP3K7 | |
| SCHEMBL13634547 | 0.89 | MAP3K7 (0.39) | SMN1; SMN2MEN1KMT2ASCDPIM1 | |
| SCHEMBL13634882 | 0.89 | MAP3K7 (0.39) | RAB9ANPC1SCDPIM1MAP3K7 | |
| SCHEMBL13634849 | 0.87 | GPR6 (0.41) | RAB9ANPC1SCDPIM1 | |
| SCHEMBL13634881 | 0.86 | NPC1 (0.40) | RAB9ANPC1SMN1; SMN2SCDPIM1 | |
| SCHEMBL13634653 | 0.85 | HRH3 (0.41) | RAB9ANPC1SMN1; SMN2SCD | |
| SCHEMBL13634883 | 0.81 | NPC1 (0.43) | NPC1MAPK1PIM1 | |
| SCHEMBL13634698 | 0.81 | MAP3K7 (0.47) | SCDMAP3K7 | |
| SCHEMBL13634648 | 0.81 | MAP3K7 (0.51) | MAP3K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |