Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 5/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.41 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.41 |
| ▸ | GPX4 | P36969 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638941 | 0.92 | MAP3K7 (0.43) | MAP3K7IRAK4FGFR1TTKGPR6 | |
| SCHEMBL13634698 | 0.92 | MAP3K7 (0.47) | MAP3K7IRAK4FGFR1GPR6 | |
| SCHEMBL13634863 | 0.91 | MAP3K7 (0.48) | MAP3K7IRAK4FGFR1GPR6 | |
| SCHEMBL13634679 | 0.89 | IRAK4 (0.43) | IRAK4CHEK1GPR6 | |
| SCHEMBL13634606 | 0.89 | IRAK4 (0.43) | IRAK4CHEK1GPR6 | |
| SCHEMBL13634620 | 0.89 | SCD (0.46) | MAP3K7IRAK4EGFRLRRK2FGFR1 | |
| SCHEMBL13634736 | 0.89 | MAP3K7 (0.40) | MAP3K7IRAK4FGFR1GPR6 | |
| SCHEMBL13634619 | 0.85 | SCN9A (0.43) | IRAK4CHEK1GPR6 | |
| SCHEMBL13634703 | 0.85 | PDE4D (0.42) | IRAK4CHEK1GPR6 | |
| SCHEMBL13634803 | 0.84 | IRAK4 (0.43) | IRAK4CHEK1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |