Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634623 | 0.96 | PIM1 (0.44) | PIM1TGFBR1IRAK4SMONAMPT | |
| SCHEMBL13634544 | 0.92 | MEN1 (0.40) | PIM1IRAK4MEN1KMT2AGPR6 | |
| SCHEMBL13634625 | 0.92 | MEN1 (0.40) | PIM1IRAK4MEN1KMT2AGPR6 | |
| SCHEMBL13634837 | 0.92 | PIM1 (0.40) | PIM1TGFBR1IRAK4SMONAMPT | |
| SCHEMBL13634770 | 0.89 | PIM1 (0.36) | PIM1IRAK4PIM3PIM2GPR6 | |
| SCHEMBL13634631 | 0.88 | GPR6 (0.40) | PIM1IRAK4SMONAMPTMEN1 | |
| SCHEMBL13634630 | 0.88 | GPR6 (0.40) | PIM1IRAK4SMONAMPTMEN1 | |
| SCHEMBL13634505 | 0.87 | PIM1 (0.35) | PIM1TGFBR1IRAK4PIM3PIM2 | |
| SCHEMBL13634504 | 0.87 | PIM1 (0.37) | PIM1IRAK4PIM3PIM2GPR6 | |
| SCHEMBL13634796 | 0.87 | GPR6 (0.37) | PIM1TGFBR1IRAK4NAMPTPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |