Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 5/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.36 |
| ▸ | GPR6 | P46095 | 6/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634770 | 0.92 | PIM1 (0.36) | PIM1PIM3PIM2IRAK4GPR6 | |
| SCHEMBL13634860 | 0.91 | POLB (0.43) | LMNAPOLBSMN1; SMN2 | |
| SCHEMBL13634505 | 0.91 | PIM1 (0.35) | PIM1PIM3PIM2IRAK4GPR6 | |
| SCHEMBL13634796 | 0.89 | GPR6 (0.37) | PIM1PIM3PIM2IRAK4GPR6 | |
| SCHEMBL13638767 | 0.88 | KDM4E (0.39) | PIM1PIM3PIM2IRAK4GPR6 | |
| SCHEMBL13634622 | 0.87 | PIM1 (0.48) | PIM1PIM3PIM2IRAK4GPR6 | |
| SCHEMBL13634840 | 0.87 | PIM1 (0.37) | PIM1PIM3PIM2IRAK4GPR6 | |
| SCHEMBL13634506 | 0.87 | PIM1 (0.39) | PIM1PIM3PIM2IRAK4PRKCA | |
| SCHEMBL13634839 | 0.86 | PIM1 (0.39) | PIM1PIM3PIM2IRAK4PRKCA | |
| SCHEMBL13634623 | 0.86 | PIM1 (0.44) | PIM1IRAK4GPR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |