Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.44 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634837 | 0.96 | PIM1 (0.40) | PIM1GPR6TGFBR1PDE10ASMO | |
| SCHEMBL13634622 | 0.96 | PIM1 (0.48) | PIM1GPR6TGFBR1SMOIRAK4 | |
| SCHEMBL13634631 | 0.92 | GPR6 (0.40) | PIM1GPR6SMOIRAK4GRM4 | |
| SCHEMBL13634630 | 0.92 | GPR6 (0.40) | PIM1GPR6SMOIRAK4GRM4 | |
| SCHEMBL13634625 | 0.88 | MEN1 (0.40) | PIM1GPR6IRAK4GRM4 | |
| SCHEMBL13634544 | 0.88 | MEN1 (0.40) | PIM1GPR6IRAK4GRM4 | |
| SCHEMBL13634770 | 0.87 | PIM1 (0.36) | PIM1GPR6IRAK4 | |
| SCHEMBL13634505 | 0.86 | PIM1 (0.35) | PIM1GPR6TGFBR1IRAK4 | |
| SCHEMBL13634504 | 0.86 | PIM1 (0.37) | PIM1GPR6IRAK4 | |
| SCHEMBL13634796 | 0.86 | GPR6 (0.37) | PIM1GPR6TGFBR1PDE10AIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |