Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634544 | 1.00 | MEN1 (0.40) | MEN1KMT2AIRAK4PIM1SMN1; SMN2 | |
| SCHEMBL13634631 | 0.95 | GPR6 (0.40) | MEN1KMT2AIRAK4PIM1GRM4 | |
| SCHEMBL13634630 | 0.95 | GPR6 (0.40) | MEN1KMT2AIRAK4PIM1GRM4 | |
| SCHEMBL13634622 | 0.92 | PIM1 (0.48) | MEN1KMT2AIRAK4PIM1GPR6 | |
| SCHEMBL13634787 | 0.88 | HCAR2 (0.40) | MEN1KMT2AIRAK4SMN1; SMN2ALDH1A1 | |
| SCHEMBL13270803 | 0.88 | HCAR2 (0.40) | MEN1KMT2AIRAK4SMN1; SMN2ALDH1A1 | |
| SCHEMBL13634623 | 0.88 | PIM1 (0.44) | IRAK4PIM1GRM4GPR6 | |
| SCHEMBL13634890 | 0.87 | ALDH1A1 (0.37) | KMT2AIRAK4SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13634860 | 0.87 | POLB (0.43) | KMT2ASMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL13634726 | 0.86 | GPR6 (0.38) | MEN1KMT2AIRAK4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |