Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 8/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634900 | 0.94 | GRM2 (0.42) | GRM2IRAK4DRD4MAPK1SMN1; SMN2 | |
| SCHEMBL13634742 | 0.91 | KMT2A (0.45) | GRM2IRAK4DRD4HRH3LMNA | |
| SCHEMBL13634629 | 0.91 | GRM2 (0.40) | GRM2IRAK4DRD4SMN1; SMN2HRH3 | |
| SCHEMBL13634797 | 0.83 | IRAK4 (0.50) | IRAK4MAPK1LMNAMAPT | |
| SCHEMBL13634721 | 0.80 | IRAK4 (0.49) | GRM2IRAK4MAPK1MAPT | |
| SCHEMBL13270468 | 0.79 | IRAK4 (0.46) | IRAK4MAPK1ACHELMNAMAPT | |
| SCHEMBL13634784 | 0.75 | IRAK4 (0.51) | IRAK4SMN1; SMN2LMNAMAPT | |
| SCHEMBL2772428 | 0.75 | SMN1; SMN2 (0.44) | IRAK4MAPK1SMN1; SMN2S1PR1ACHE | |
| SCHEMBL13638973 | 0.74 | GRM2 (0.49) | GRM2DRD4LMNAMAPT | |
| SCHEMBL13634551 | 0.73 | IRAK4 (0.47) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |