Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15888629 | 0.94 | SCD (0.32) | SCDSCD5WDR5GRM2CNR2 | |
| SCHEMBL13270650 | 0.91 | MAPT (0.39) | SCDSCD5IRAK4MEN1ALDH1A1 | |
| SCHEMBL13638833 | 0.89 | GRM2 (0.39) | SCDSCD5GRM2MCHR1PARP1 | |
| SCHEMBL13634738 | 0.87 | GRM2 (0.35) | SCDSCD5GRM2ALDH1A1KMT2A | |
| SCHEMBL3127604 | 0.87 | IRAK4 (0.36) | SCDSCD5IRAK4GRM2MEN1 | |
| SCHEMBL13634767 | 0.86 | SCD (0.37) | SCDSCD5CNR2PIM1PIM3 | |
| SCHEMBL13634757 | 0.86 | MAPT (0.40) | IRAK4MEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13634559 | 0.86 | ALDH1A1 (0.41) | MEN1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13634927 | 0.85 | CNR2 (0.36) | SCDSCD5CNR2PIM1PIM3 | |
| SCHEMBL13162737 | 0.84 | GRM2 (0.36) | SCDSCD5GRM2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |