Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634606 | 0.85 | IRAK4 (0.43) | IRAK4LMNANPSR1CHEK1PDE4D | |
| SCHEMBL13634679 | 0.85 | IRAK4 (0.43) | IRAK4LMNANPSR1CHEK1PDE4D | |
| SCHEMBL13634648 | 0.84 | MAP3K7 (0.51) | IRAK4LRRK2CHEK1 | |
| SCHEMBL13634619 | 0.82 | SCN9A (0.43) | IRAK4CHEK1PDE4DSCDHPGD | |
| SCHEMBL13634703 | 0.81 | PDE4D (0.42) | IRAK4CHEK1PDE4DSCDHPGD | |
| SCHEMBL13634680 | 0.80 | POLB (0.42) | IRAK4LRRK2CHEK1PDE4DSCD | |
| SCHEMBL13638935 | 0.78 | SCD (0.44) | IRAK4LMNACHEK1SCDHPGD | |
| SCHEMBL13634598 | 0.78 | HRH3 (0.42) | IRAK4CHEK1SCD | |
| SCHEMBL13634653 | 0.77 | HRH3 (0.41) | IRAK4CHEK1SCD | |
| SCHEMBL13638941 | 0.77 | MAP3K7 (0.43) | IRAK4SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |