Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162410 | 0.79 | MEN1 (0.54) | THRBL3MBTL1HPGDCYP1A2CYP2C19 | |
| SCHEMBL29018044 | 0.79 | CTSD (0.56) | HPGDCYP1A2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL29018041 | 0.79 | CTSD (0.56) | HPGDCYP1A2CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL5221653 | 0.76 | HPGD (0.56) | THRBL3MBTL1HPGDCYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL4682469 | 0.76 | HPGD (0.47) | THRBL3MBTL1HPGDCYP1A2CYP2C19 | |
| SCHEMBL10657352 | 0.76 | L3MBTL1 (0.52) | THRBL3MBTL1HPGDSMN1; SMN2GAA | |
| SCHEMBL18419393 | 0.76 | L3MBTL1 (0.52) | THRBL3MBTL1HPGDSMN1; SMN2GAA | |
| SCHEMBL13162409 | 0.76 | TAS1R3 (0.51) | THRBL3MBTL1HPGDLMNAMEN1 | |
| SCHEMBL19813081 | 0.75 | HPGD (0.56) | THRBL3MBTL1HPGDLMNASMN1; SMN2 | |
| SCHEMBL4682849 | 0.75 | CNR2 (0.50) | THRBL3MBTL1HPGDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |