Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 2/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634898 | 0.92 | GPR6 (0.37) | GPR6SCDOPRK1KMT2APTPN1 | |
| SCHEMBL13634719 | 0.92 | HRH3 (0.39) | GPR6SCDOPRK1KCNH2KMT2A | |
| SCHEMBL13634583 | 0.90 | GLS (0.39) | GPR6SCDOPRK1KMT2AHDAC3 | |
| SCHEMBL13638989 | 0.89 | MCHR1 (0.35) | GPR6SCDOPRK1KMT2AMCHR1 | |
| SCHEMBL2770731 | 0.89 | OPRK1 (0.42) | OPRK1KMT2AMCHR1 | |
| SCHEMBL13634794 | 0.86 | HRH3 (0.38) | GPR6SCDOPRK1KMT2APTPN1 | |
| SCHEMBL13270466 | 0.84 | SCD (0.35) | GPR6SCDPRSS12CYP2C9CYP2C19 | |
| SCHEMBL13634832 | 0.83 | GPR6 (0.39) | GPR6SCDOPRK1KMT2AHDAC3 | |
| SCHEMBL13634716 | 0.83 | HRH3 (0.40) | GPR6SCDOPRK1KMT2APTPN1 | |
| SCHEMBL13638883 | 0.83 | MCHR1 (0.35) | GPR6SCDOPRK1KMT2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |