Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 6/20 | 0.42 |
| ▸ | GPR6 | P46095 | 10/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2770136 | 0.92 | GPR6 (0.42) | PIM1GPR6SCDPIM3PIM2 | |
| SCHEMBL13634783 | 0.82 | IRAK4 (0.48) | — | |
| SCHEMBL2770451 | 0.81 | GPR6 (0.43) | PIM1GPR6SCDCHEK1 | |
| SCHEMBL13634849 | 0.80 | GPR6 (0.41) | PIM1GPR6SCDCHEK1 | |
| SCHEMBL13634609 | 0.80 | GPR6 (0.41) | GPR6SCDCHEK1 | |
| SCHEMBL13162054 | 0.80 | SCD (0.50) | PIM1GPR6SCD | |
| SCHEMBL2772627 | 0.80 | SCD (0.50) | SCD | |
| SCHEMBL13634696 | 0.80 | GPR6 (0.38) | GPR6SCDCHEK1 | |
| SCHEMBL13634679 | 0.80 | IRAK4 (0.43) | GPR6SCDCHEK1 | |
| SCHEMBL2770731 | 0.80 | OPRK1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206707-B1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2010-09-30 | — | — | US | disclosed |
| EP-2206707-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249088-A1 | AZOLECARBOXAMIDE COMPOUND OR SALT THEREOF | TRPV1, FGFR3, GPR17 | PIM1 913/4885GPR6 775/4885SCD 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.