Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 8/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.34 |
| ▸ | USP25 | Q9UHP3 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638952 | 0.94 | CHEK1 (0.37) | CHEK1HDAC3HDAC2PIN1USP25 | |
| SCHEMBL13634910 | 0.88 | PIN1 (0.35) | CHEK1PIN1 | |
| SCHEMBL13634760 | 0.86 | GLS (0.40) | CHEK1PIN1 | |
| SCHEMBL13634933 | 0.85 | PDE4B (0.41) | — | |
| SCHEMBL13634658 | 0.85 | GLS (0.40) | PIN1 | |
| SCHEMBL13634751 | 0.85 | GLS (0.39) | CHEK1PIN1 | |
| SCHEMBL13634924 | 0.85 | GLS (0.39) | CHEK1PIN1 | |
| SCHEMBL13634923 | 0.85 | CHEK1 (0.36) | CHEK1HDAC3HDAC2 | |
| SCHEMBL13634574 | 0.85 | CHEK1 (0.36) | CHEK1HDAC3HDAC2 | |
| SCHEMBL13634918 | 0.84 | GLS (0.39) | CHEK1PIN1USP25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |