Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | PAICS | P22234 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634916 | 0.93 | GPR6 (0.42) | GPR6ALDH1A1IRAK4FGFR1 | |
| SCHEMBL13634570 | 0.91 | GPR6 (0.40) | GPR6ALDH1A1IRAK4KDM4EHPGD | |
| SCHEMBL13634635 | 0.89 | PIM1 (0.45) | GPR6ALDH1A1IRAK4 | |
| SCHEMBL13634508 | 0.82 | ALDH1A1 (0.41) | GPR6ALDH1A1PAICSFGFR1 | |
| SCHEMBL13634510 | 0.81 | NAMPT (0.37) | GPR6ALDH1A1KDM4EPAICSFGFR1 | |
| SCHEMBL13634511 | 0.81 | NAMPT (0.37) | GPR6ALDH1A1KDM4EPAICSFGFR1 | |
| SCHEMBL13634676 | 0.81 | GPR6 (0.42) | GPR6PAICS | |
| SCHEMBL13634835 | 0.81 | PIM1 (0.42) | GPR6ALDH1A1PAICS | |
| SCHEMBL13634580 | 0.80 | GPR6 (0.36) | GPR6PAICSFGFR1 | |
| SCHEMBL13634512 | 0.80 | SCD (0.39) | GPR6PAICSFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |