Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 10/20 | 0.38 |
| ▸ | GPR6 | P46095 | 3/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634872 | 0.89 | GPR6 (0.41) | IRAK4GPR6ALDH1A1 | |
| SCHEMBL13634570 | 0.88 | GPR6 (0.40) | TGFBR1IRAK4GPR6MAPK14ALDH1A1 | |
| SCHEMBL13634916 | 0.88 | GPR6 (0.42) | IRAK4GPR6ALDH1A1 | |
| SCHEMBL13634835 | 0.86 | PIM1 (0.42) | PIM1GPR6ALDH1A1 | |
| SCHEMBL13634798 | 0.84 | PIM1 (0.48) | PIM1IRAK4GPR6 | |
| SCHEMBL13634673 | 0.82 | PIM1 (0.43) | PIM1IRAK4GPR6 | |
| SCHEMBL13634792 | 0.81 | PDE10A (0.46) | PIM1TGFBR1IRAK4GPR6 | |
| SCHEMBL13634671 | 0.81 | PDE10A (0.46) | PIM1TGFBR1IRAK4GPR6 | |
| SCHEMBL13634622 | 0.81 | PIM1 (0.48) | PIM1TGFBR1IRAK4GPR6 | |
| SCHEMBL13634507 | 0.81 | CNR2 (0.43) | PIM1IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |