Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 2/20 | 0.36 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638771 | 0.94 | SCD (0.36) | SCDSCD5PARP1TNK1HDAC6 | |
| SCHEMBL13634657 | 0.92 | DRD4 (0.41) | GLSSCDSCD5DRD4PARP1 | |
| SCHEMBL13634656 | 0.92 | DRD4 (0.41) | GLSSCDSCD5DRD4PARP1 | |
| SCHEMBL13634563 | 0.91 | PDCD1 (0.37) | GLSSCDSCD5DRD4PARP1 | |
| SCHEMBL13634884 | 0.91 | S1PR1 (0.40) | DRD4KDM4EALDH1A1S1PR1 | |
| SCHEMBL13634886 | 0.90 | ACKR3 (0.38) | GLSSCDSCD5DRD4PARP1 | |
| SCHEMBL13634915 | 0.90 | LMNA (0.37) | GLSSCDSCD5DRD4PARP1 | |
| SCHEMBL13634760 | 0.89 | GLS (0.40) | GLSSCDSCD5PIN1NAPEPLD | |
| SCHEMBL13634751 | 0.88 | GLS (0.39) | GLSSCDSCD5PARP1TNK1 | |
| SCHEMBL13634924 | 0.88 | GLS (0.39) | GLSSCDSCD5PIN1NAPEPLD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |