Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.36 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DNM1L | O00429 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 2/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13634563 | 0.96 | PDCD1 (0.37) | LMNATP53PARP1TNK1GLS | |
| SCHEMBL13634887 | 0.90 | GLS (0.36) | LMNAPARP1TNK1METTL3GLS | |
| SCHEMBL13634886 | 0.89 | ACKR3 (0.38) | PARP1TNK1GLSDRD4PDCD1 | |
| SCHEMBL13634656 | 0.89 | DRD4 (0.41) | PARP1TNK1GLSS1PR1DRD4 | |
| SCHEMBL13634657 | 0.89 | DRD4 (0.41) | PARP1TNK1GLSS1PR1DRD4 | |
| SCHEMBL13634884 | 0.89 | S1PR1 (0.40) | S1PR1DRD4KMT2AALDH1A1KDM4E | |
| SCHEMBL13634760 | 0.88 | GLS (0.40) | TP53HRH3GLSSCDSCD5 | |
| SCHEMBL13634738 | 0.88 | GRM2 (0.35) | LMNATP53PARP1TNK1PDCD1 | |
| SCHEMBL2770055 | 0.88 | PARP1 (0.38) | PARP1TNK1GLSSCDSCD5 | |
| SCHEMBL13634924 | 0.88 | GLS (0.39) | HRH3GLSSCDSCD5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |