Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28084079 | 0.86 | DNM1 (0.43) | LMNAALDH1A1TDP1CYP3A4 | |
| SCHEMBL2216199 | 0.86 | ALDH1A1 (0.46) | LMNAALDH1A1TDP1OPRM1SPHK1 | |
| SCHEMBL6011981 | 0.85 | LMNA (0.46) | LMNAALDH1A1TDP1OPRM1SPHK1 | |
| SCHEMBL11127804 | 0.84 | LMNA (0.40) | LMNASPHK1TRPV1TRPA1 | |
| SCHEMBL5505106 | 0.84 | LMNA (0.50) | LMNAALDH1A1TDP1OPRM1SPHK1 | |
| SCHEMBL14612506 | 0.84 | LMNA (0.50) | LMNAALDH1A1TDP1OPRM1SPHK1 | |
| SCHEMBL11127805 | 0.84 | LMNA (0.40) | LMNASPHK1TRPV1TRPA1 | |
| SCHEMBL11609968 | 0.84 | LMNA (0.50) | LMNAALDH1A1TDP1OPRM1SPHK1 | |
| SCHEMBL117273 | 0.84 | LMNA (0.50) | LMNAALDH1A1TDP1OPRM1SPHK1 | |
| SCHEMBL11319259 | 0.84 | LMNA (0.40) | LMNASPHK1TRPV1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275881-A1 | OPTIMIZING THERAPY OUTCOMES FOR PERITONEAL DIALYSIS | BAXTER INTERNATIONAL INC. (US) | 2009-11-05 | — | — | US | disclosed |