Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12376076 | 0.84 | MAOA (0.33) | TLR4 | |
| SCHEMBL13635242 | 0.84 | DRD2 (0.34) | TLR4 | |
| SCHEMBL12375971 | 0.83 | MAOA (0.34) | TLR4 | |
| SCHEMBL12376139 | 0.79 | — | — | |
| SCHEMBL12375807 | 0.79 | TLR4 (0.32) | TLR4 | |
| SCHEMBL12376156 | 0.79 | — | — | |
| SCHEMBL12375820 | 0.78 | TLR4 (0.32) | TLR4 | |
| SCHEMBL13635336 | 0.78 | GPR119 (0.35) | FYNTLR4 | |
| SCHEMBL12376131 | 0.77 | — | — | |
| SCHEMBL12376148 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409441-B1 | INDANE COMPOUNDS WITH NEGATIVE DIELECTRIC ANISOTROPY | MERCK PATENT GMBH (DE) | 2009-11-18 | — | — | EP | disclosed |