Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.34 |
| ▸ | DRD3 | P35462 | 6/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635372 | 0.84 | FYN (0.31) | TLR4 | |
| SCHEMBL13635336 | 0.81 | GPR119 (0.35) | TLR4 | |
| SCHEMBL12376076 | 0.76 | MAOA (0.33) | OPRL1OPRM1OPRK1TLR4 | |
| Hydrochloric Acid SCHEMBL2589524 | 0.74 | SLC6A2 (0.35) | DRD2DRD3HTR1APRKAB2PRKAG1 | |
| SCHEMBL12375971 | 0.74 | MAOA (0.34) | OPRL1OPRM1OPRK1TLR4 | |
| SCHEMBL12622304 | 0.72 | CYP2C9 (0.32) | OPRL1TLR4 | |
| SCHEMBL17075718 | 0.72 | OPRL1 (0.46) | OPRL1HTR1ATLR4 | |
| SCHEMBL17075724 | 0.72 | OPRL1 (0.46) | OPRL1HTR1ATLR4 | |
| SCHEMBL17075722 | 0.72 | OPRL1 (0.46) | OPRL1HTR1ATLR4 | |
| SCHEMBL13635239 | 0.72 | DRD2 (0.34) | DRD2DRD3OPRL1HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409441-B1 | INDANE COMPOUNDS WITH NEGATIVE DIELECTRIC ANISOTROPY | MERCK PATENT GMBH (DE) | 2009-11-18 | — | — | EP | disclosed |