Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13011491 | 1.00 | SCARB1 (0.45) | SCARB1KIF11PTGER4ADRA1DADRA1A | |
| SCHEMBL13011492 | 1.00 | SCARB1 (0.45) | SCARB1KIF11PTGER4ADRA1DADRA1A | |
| SCHEMBL3783032 | 0.93 | SCARB1 (0.44) | SCARB1KIF11PTGER4ADRA1DADRA1A | |
| SCHEMBL13011495 | 0.87 | KDM4E (0.49) | PTGER4PARP1ALDH1A1LMNAMAPT | |
| SCHEMBL13011493 | 0.87 | KDM4E (0.49) | PTGER4PARP1ALDH1A1LMNAMAPT | |
| SCHEMBL3774230 | 0.84 | HSD11B1 (0.44) | SCARB1KIF11PTGER4ADRA1DADRA1A | |
| SCHEMBL3780734 | 0.84 | HSD11B1 (0.44) | SCARB1KIF11CNR2HSD11B1PARP1 | |
| SCHEMBL3805093 | 0.84 | ALDH1A1 (0.43) | SCARB1KIF11PTGER4ADRA1DADRA1A | |
| SCHEMBL13011205 | 0.83 | ALDH1A1 (0.51) | SCARB1KIF11PTGER4EGFRSRC | |
| SCHEMBL13635205 | 0.83 | ALDH1A1 (0.51) | SCARB1KIF11PTGER4EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119704-A1 | ACYLGUANIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2009-11-18 | — | — | EP | disclosed |