Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | AXL | P30530 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385079 | 0.88 | MAPK14 (0.51) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13635755 | 0.77 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4480210 | 0.75 | MAPT (0.56) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4467899 | 0.75 | MAPT (0.54) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4378804 | 0.75 | MAPK14 (0.56) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL3521076 | 0.73 | MAPT (0.49) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL13635320 | 0.72 | POLB (0.49) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4476536 | 0.72 | MAPK14 (0.55) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4390042 | 0.70 | SMN1; SMN2 (0.52) | L3MBTL1ALDH1A1KDM4ESMN1; SMN2MEN1 | |
| SCHEMBL4466743 | 0.69 | MAPK14 (0.60) | L3MBTL1ALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490064-B1 | SUBSTITUTED PYRIDINONES AS MODULATORS OF P38 MAP KINASE | PHARMACIA CORP (US) | 2009-11-18 | — | — | EP | disclosed |