Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 4/20 | 0.34 |
| ▸ | EYA2 | O00167 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19458 | 0.90 | TDP1 (0.42) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL19543084 | 0.84 | TDP1 (0.48) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL4621864 | 0.83 | TDP1 (0.58) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL438113 | 0.83 | TDP1 (0.58) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL7567960 | 0.83 | CHRM2 (0.37) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL992084 | 0.83 | TDP1 (0.58) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL29484958 | 0.83 | CA14 (0.38) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL13787056 | 0.81 | TDP1 (0.35) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL15178401 | 0.81 | TDP1 (0.35) | TDP1KDM4ELMNACHRM2ADRA2A | |
| SCHEMBL24896787 | 0.81 | NR1D1 (0.33) | TDP1KDM4ELMNACHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8562953-B2 | Dendritic polymers and magnetic resonance imaging contrast agent employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-10-22 | — | — | US | disclosed |
| US-20130030139-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2013-01-31 | — | — | US | disclosed |
| US-8303937-B2 | Dendritic polymers and magnetic resonance imaging contrast agent employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-11-06 | — | — | US | disclosed |
| US-20090169480-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-07-02 | — | — | US | disclosed |
| US-20090169481-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2009-07-02 | — | — | US | disclosed |
| US-20070154390-A1 | Nuclear molecular imaging contrast agent | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE | 2007-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070154390-A1 | Nuclear molecular imaging contrast agent | H1-3, H1-10, H1-4 | TDP1 2842/4885KDM4E 3290/4885LMNA 1586/4885 |
| US-20090169481-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | DCLK1, MSR1, S1PR3 | TDP1 3487/4885KDM4E 2887/4885LMNA 2032/4885 |
| US-20090169480-A1 | DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME | CD14, DCUN1D3, CCR3 | TDP1 4571/4885KDM4E 2005/4885LMNA 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.