Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | DRD5 | P21918 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | THPO | P40225 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1655398 | 0.82 | IAPP (0.56) | ALOX15MAPTKDM4EMAPK1ADRA2A | |
| SCHEMBL29997235 | 0.82 | IAPP (0.56) | ALOX15MAPTKDM4EMAPK1ADRA2A | |
| SCHEMBL19199480 | 0.82 | ALOX15 (0.59) | ALOX15MAPTKDM4EMAPK1ADRA2A | |
| SCHEMBL15177992 | 0.80 | ALOX15 (0.63) | ALOX15MAPTKDM4EMAPK1ADRA2A | |
| SCHEMBL925636 | 0.80 | IAPP (0.62) | ALOX15MAPTKDM4EMAPK1ADRA2A | |
| SCHEMBL30986806 | 0.80 | IAPP (0.62) | ALOX15MAPTKDM4EMAPK1ADRA2A | |
| SCHEMBL14548001 | 0.80 | ALOX15 (0.57) | ALOX15MAPTKDM4EMAPK1ADRA2A | |
| Hydrochloric Acid SCHEMBL10340417 | 0.78 | IAPP (0.61) | ALOX15MAPTKDM4EMAPK1ADRA2A | |
| SCHEMBL107956 | 0.78 | ALOX15 (0.80) | ALOX15MAPTKDM4EMAPK1ADRA2A | |
| SCHEMBL30631592 | 0.78 | ALOX15 (0.80) | ALOX15MAPTKDM4EMAPK1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1421071-B1 | SUBSTITUTED PIPERAZINE AND DIAZEPANE DERIVAIVES AS HISTAMINE H3 RECEPTOR MODULATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2009-11-18 | — | — | EP | disclosed |