Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.62 |
| ▸ | APP | P05067 | 2/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | TYR | P14679 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.59 |
| ▸ | DRD2 | P14416 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 2/20 | 0.59 |
| ▸ | DRD4 | P21917 | 2/20 | 0.59 |
| ▸ | DRD5 | P21918 | 2/20 | 0.59 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | DRD3 | P35462 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30986806 | 1.00 | IAPP (0.62) | IAPPAPPCYP19A1TYRKDM4E | |
| Hydrochloric Acid SCHEMBL10340417 | 0.98 | IAPP (0.61) | IAPPAPPCYP19A1TYRKDM4E | |
| SCHEMBL29381000 | 0.90 | ALOX15 (0.67) | IAPPAPPKDM4EMAPTTDP1 | |
| SCHEMBL6346995 | 0.90 | ALOX15 (0.67) | IAPPAPPKDM4EMAPTTDP1 | |
| SCHEMBL6340368 | 0.87 | ALOX15 (0.68) | IAPPKDM4EMAPTTDP1ALDH1A1 | |
| SCHEMBL24854636 | 0.86 | CNR1 (0.55) | IAPPAPPCYP19A1TYRKDM4E | |
| SCHEMBL28165571 | 0.83 | IAPP (0.82) | IAPPAPPCYP19A1TYRKDM4E | |
| SCHEMBL28022655 | 0.83 | CA2 (0.56) | IAPPAPPCYP19A1TYRHSD17B10 | |
| SCHEMBL23476677 | 0.83 | HIF1A (0.49) | IAPPAPPCYP19A1TYRKDM4E | |
| SCHEMBL28659512 | 0.83 | ESR1 (0.55) | IAPPAPPCYP19A1TYRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644772-A4 | OPIOID PEPTIDES. | BIOMEASURE INC (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0644772-A1 | OPIOID PEPTIDES | BIOMEASURE, INC. (US) | 1995-03-29 | — | — | EP | claimed |
| WO-1994011018-A1 | OPIOID PEPTIDES | BIOMEASURE, INC. (US) | 1994-05-26 | — | — | WO | claimed |
| JP-2053767-A | — | — | None | — | — | JP | disclosed |
| JP-5032646-A | — | — | None | — | — | JP | disclosed |
| EP-4192824-A1 | THERAPEUTIC COMPOSITION OF CURE-PRO COMPOUNDS FOR TARGETED DEGRADATION OF BET DOMAIN PROTEINS, AND METHODS OF MAKING AND USAGE | Cornell University (US) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022031772-A1 | THERAPEUTIC COMPOSITION OF CURE-PRO COMPOUNDS FOR TARGETED DEGRADATION OF BET DOMAIN PROTEINS, AND METHODS OF MAKING AND USAGE | CORNELL UNIVERSITY (US) | 2022-02-10 | — | — | WO | disclosed |
| CN-109310649-B | Dihydrochalcone derivatives affecting inflammatory states | 西姆莱斯有限公司 | 2021-06-29 | — | — | CN | disclosed |
| US-10758468-B2 | Solubilizer for cosmetic preparations | SYMRISE AG (DE) | 2020-09-01 | — | — | US | disclosed |
| CN-108495617-A | Including the pharmaceutical composition of levodopa amide and its purposes | 纽罗德姆有限公司 | 2018-09-04 | — | — | CN | disclosed |
| US-20170312384-A9 | MULTIBRANCHED BIOADHESIVE COMPOUNDS AND SYNTHETIC METHODS THEREFOR | DSM IP ASSETS B.V. (NL) | 2017-11-02 | — | — | US | disclosed |
| US-20030171617-A1 | 3,4-Dihydroxymandelic acid alkylamides and use thereof | HAARMANN & REIMER GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
| US-20030139470-A1 | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | HAARMANN & REIMER GMBH (DE) | 2003-07-24 | — | — | US | disclosed |
| US-20030072725-A1 | Topical cosmetic agents containing 2-hydrazino-1,3 -heteroazoles | HAARMANN & REIMER GMBH (DE) | 2003-04-17 | — | — | US | disclosed |
| US-20030049287-A1 | Catechol oximes and their use in cosmetic and dermatological preparations | HAARMANN & REIMER GMBH (DE) | 2003-03-13 | — | — | US | disclosed |
| JP-H0532646-A | DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND USE THEREOF FOR MEDICINE | MITSUI TOATSU CHEM INC | 1993-02-09 | — | — | JP | disclosed |
| EP-0495998-A1 | DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-29 | — | — | EP | disclosed |
| WO-1992002490-A1 | DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-02-20 | — | — | WO | disclosed |
| JP-H0253767-A | DIHYDROCAFFEIC ACID AMIDE COMPOUND AND REMEDY CONAINING THE SAME AMIDE AS ACTIVE INGREDIENT | MITSUI TOATSU CHEM INC | 1990-02-22 | — | — | JP | disclosed |
| US-4448730-A | ANTITUMOR AGENTS | RIET BARTHOLOMEUS VAN T | 1984-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10758468-B2 | Solubilizer for cosmetic preparations | SRPK3, SRPK1, SYMPK | IAPP 3938/4885APP 3387/4885CYP19A1 1923/4885 |
| US-20030171617-A1 | 3,4-Dihydroxymandelic acid alkylamides and use thereof | HNMT, HTR2A, HTR2C | IAPP 1464/4885APP 2858/4885CYP19A1 1197/4885 |
| US-20030049287-A1 | Catechol oximes and their use in cosmetic and dermatological preparations | TYR, LPO, COMT | IAPP 4690/4885APP 3260/4885CYP19A1 47/4885 |
| US-20030139470-A1 | 3,4-dihydroxybenzyl-substituted carbonic acid derivatives and the use thereof as antioxidants | TYR, HAAO, TH | IAPP 1938/4885APP 1138/4885CYP19A1 140/4885 |
| US-20030072725-A1 | Topical cosmetic agents containing 2-hydrazino-1,3 -heteroazoles | TYR, MITF, HDAC1 | IAPP 4837/4885APP 4317/4885CYP19A1 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.