Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.57 |
| ▸ | IGF1R | P08069 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | THPO | P40225 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 2/20 | 0.53 |
| ▸ | DRD5 | P21918 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14548002 | 0.93 | ALOX15 (0.62) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL15866316 | 0.86 | ALOX5 (0.62) | ALOX15ALDH1A1GAAALOX5MAPK1 | |
| SCHEMBL19199480 | 0.82 | ALOX15 (0.59) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL15177992 | 0.80 | ALOX15 (0.63) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL13636197 | 0.80 | ALOX15 (0.59) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL30631592 | 0.78 | ALOX15 (0.80) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL107956 | 0.78 | ALOX15 (0.80) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| Didemethyltetrahydrocurcumin SCHEMBL6344877 | 0.76 | IAPP (0.73) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL3383712 | 0.76 | IAPP (0.57) | ALOX15IGF1RMAPTKDM4EALDH1A1 | |
| SCHEMBL8431254 | 0.75 | ALOX15 (0.76) | ALOX15IGF1RMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007043058-A1 | PROCESS FOR PRODUCING ENRICHED FRACTIONS OF TETRAHYDROXYCURCUMIN AND TETRAHYDROTETRAHYDROXY-CURCUMIN FROM THE EXTRACTS OF CURCUMA LONGA | GOKARAJU GANGA RAJU (IN) | 2007-04-19 | — | — | WO | disclosed |