SCHEMBL13636557

SCHEMBL13636557

C=C(CC)C(=O)Oc1ccc(OC(=O)C(=C)CC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.46
ESR1 P03372 2/20 0.46
HIF1A Q16665 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
RECQL P46063 1/20 0.46
MEN1 O00255 1/20 0.45
ELANE P08246 5/20 0.44
THRB P10828 2/20 0.42
ATM Q13315 1/20 0.41
LMNA P02545 2/20 0.41
ALDH1A1 P00352 2/20 0.41
MAPT P10636 2/20 0.41
HTT P42858 1/20 0.41
HSD17B10 Q99714 1/20 0.41
RAB9A P51151 2/20 0.40
BCL9 O00512 1/20 0.36
CTNNB1 P35222 1/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28406802 0.92 ELANE (0.42) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL27497707 0.92 KMT2A (0.46) KMT2ASMN1; SMN2MEN1LMNAALDH1A1
SCHEMBL7079700 0.91 KMT2A (0.43) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL28061211 0.91 FAAH (0.43) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL28198215 0.91 MGLL (0.45) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL434641 0.90 ELANE (0.49) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL15834835 0.88 ELANE (0.51) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL27891771 0.88 KMT2A (0.51) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL5838271 0.88 THRB (0.41) KMT2AESR1HIF1ASMN1; SMN2RECQL
SCHEMBL28197539 0.88 F2 (0.42) KMT2AESR1HIF1ASMN1; SMN2RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304117-B2 Comprises bismaleimide oligomer formed by reaction of barbituric acid and bismaleimide INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-11-06 US disclosed
US-8304117-B2 Comprises bismaleimide oligomer formed by reaction of barbituric acid and bismaleimide INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-11-06 US disclosed
US-20080160404-A1 Gel polymer electrolyte precursor and rechargeable cell comprising the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-07-03 US disclosed
US-20080160404-A1 Gel polymer electrolyte precursor and rechargeable cell comprising the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE 2008-07-03 US disclosed