Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13636557 | 0.91 | KMT2A (0.46) | KMT2AELANEMEN1SMN1; SMN2MAPT | |
| SCHEMBL28406802 | 0.84 | ELANE (0.42) | KMT2ACYP1A2CYP2D6CYP2C19ELANE | |
| SCHEMBL27497707 | 0.84 | KMT2A (0.46) | KMT2ACYP1A2CYP2C19CYP2C9MEN1 | |
| SCHEMBL28061211 | 0.82 | FAAH (0.43) | KMT2ACYP1A2CYP2C19CYP2C9ELANE | |
| SCHEMBL28198215 | 0.82 | MGLL (0.45) | KMT2AELANEMEN1SMN1; SMN2MAPT | |
| SCHEMBL4828996 | 0.82 | ELANE (0.39) | KMT2ACYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL434641 | 0.81 | ELANE (0.49) | KMT2AELANEHPGDSMN1; SMN2MAPT | |
| SCHEMBL27546455 | 0.81 | KMT2A (0.45) | KMT2ACYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL9355225 | 0.81 | KMT2A (0.46) | KMT2AELANECYP11B1CYP11B2MEN1 | |
| SCHEMBL452065 | 0.79 | ELANE (0.59) | KMT2ACYP1A2CYP2D6CYP2C19ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3728339-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| US-20030151825-A1 | Polyacrylate-based light adjustable optical element | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-08-14 | — | — | US | disclosed |
| WO-2003060565-A2 | POLYACRYLATE BASED LIGHT ADJUSTABLE OPTICAL ELEMENT | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-07-24 | — | — | WO | disclosed |