Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13636716 | 0.92 | NFE2L2 (0.44) | NFE2L2ARPTGS2PTGS1RPS6KA3 | |
| SCHEMBL13636578 | 0.90 | NFE2L2 (0.45) | NFE2L2ARPTGS2PTGS1CYP11B1 | |
| SCHEMBL25686111 | 0.84 | NFE2L2 (0.56) | NFE2L2PTGS2PTGS1CYP1A2CYP1A1 | |
| SCHEMBL13535962 | 0.84 | NFE2L2 (0.56) | NFE2L2PTGS2PTGS1CYP1A2CYP1A1 | |
| SCHEMBL12976570 | 0.81 | NFE2L2 (0.46) | NFE2L2ARCYP11B1CYP11B2 | |
| SCHEMBL12976347 | 0.81 | NFE2L2 (0.46) | NFE2L2ARCYP11B1CYP11B2 | |
| SCHEMBL11957388 | 0.76 | NFE2L2 (0.46) | NFE2L2PTGS2PTGS1RPS6KA3 | |
| SCHEMBL13636826 | 0.76 | PTGS2 (0.41) | NFE2L2PTGS2PTGS1RPS6KA3 | |
| SCHEMBL20888423 | 0.76 | NFE2L2 (0.46) | NFE2L2PTGS2PTGS1RPS6KA3 | |
| SCHEMBL12230850 | 0.76 | NFE2L2 (0.46) | NFE2L2PTGS2PTGS1RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2123623-A1 | LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2009-11-25 | — | — | EP | disclosed |