Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 12/20 | 0.71 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.58 |
| ▸ | NQO2 | P16083 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9849735 | 0.88 | NFE2L2 (0.91) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL29404131 | 0.85 | NFE2L2 (0.67) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL11895254 | 0.85 | NFE2L2 (0.67) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL11895252 | 0.85 | NFE2L2 (0.67) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL698584 | 0.84 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL698583 | 0.84 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL700536 | 0.83 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL31317689 | 0.83 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL700537 | 0.83 | NFE2L2 (1.00) | NFE2L2RELAPTGS1NQO2PTGS2 | |
| SCHEMBL13636750 | 0.82 | APP (0.50) | NFE2L2PTGS1NQO2PTGS2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1957605-B1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-11 | — | — | EP | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-8304095-B2 | Organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
| US-20080272693-A1 | Organic Electroluminescent Devices | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
| WO-2007065549-A1 | ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2007-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080272693-A1 | Organic Electroluminescent Devices | EML4, MT-ND4L, EPCAM | NFE2L2 423/4885RELA 2586/4885PTGS1 4105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.