Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995257 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2 | |
| SCHEMBL28176199 | 0.73 | TMEM97 (0.47) | DRD3 | |
| SCHEMBL18501012 | 0.69 | CA12 (0.35) | DRD1CA2ACHECA12CA1 | |
| SCHEMBL14748410 | 0.68 | ALDH1A1 (0.54) | CA2ACHECA12CA1CA7 | |
| SCHEMBL12093637 | 0.68 | DRD2 (0.47) | BCL2DRD1DRD5DRD2DRD3 | |
| SCHEMBL14748434 | 0.67 | PDE4A (0.50) | MAPTALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL13967007 | 0.66 | PDE4A (0.45) | BCL2DRD1DRD5DRD2DRD3 | |
| SCHEMBL6907774 | 0.65 | DRD1 (0.68) | BCL2DRD1DRD5DRD2DRD3 | |
| SCHEMBL2607471 | 0.65 | DRD1 (0.62) | BCL2DRD1DRD5DRD2DRD3 | |
| SCHEMBL6903663 | 0.65 | DRD1 (0.68) | BCL2DRD1DRD5DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140309-A2 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | WO | disclosed |