Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.65 |
| ▸ | NPC1 | O15118 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 8/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.65 |
| ▸ | RELA | Q04206 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.46 |
| ▸ | ALDH1A2 | O94788 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13643181 | 0.81 | CENPE (0.45) | ALDH1A1NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL5738406 | 0.80 | ALDH1A1 (0.72) | ALDH1A1NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL13183963 | 0.80 | CENPE (0.44) | ALDH1A1NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL14870853 | 0.80 | CENPE (0.44) | ALDH1A1NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL2617328 | 0.80 | CENPE (0.44) | ALDH1A1NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL2617338 | 0.79 | ALDH1A1 (1.00) | ALDH1A1NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL28635183 | 0.78 | NPC1 (0.74) | ALDH1A1NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL14531640 | 0.77 | NPC1 (0.72) | ALDH1A1NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL28642108 | 0.77 | NPC1 (0.72) | ALDH1A1NPC1RAB9ANFKB1NFKB2 | |
| SCHEMBL21348767 | 0.75 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9ANFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | QIAN XIANGPING (US) | 2012-11-08 | — | — | US | disclosed |
| US-20090286841-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. | 2009-11-19 | — | — | US | disclosed |
| US-7504413-B2 | N-(4-(imidazo[1,2A]pyridin-YL)phenethyl)benzamide inhibitors of the mitotic kinesin CENP-E for treating certain cellular proliferation diseases | CYTOKINETICS, INC. (US) | 2009-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090286841-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | KIF5B, KIF2C, PLK1 | ALDH1A1 2159/4885NPC1 835/4885RAB9A 1213/4885 |
| US-20120283287-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | KIF5B, KIF2C, PLK1 | ALDH1A1 2159/4885NPC1 835/4885RAB9A 1213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.