Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13637468 | 0.81 | CYP19A1 (0.64) | ALDH1A1CYP19A1AKR1C3MAPTKMT2A | |
| SCHEMBL14049770 | 0.81 | AKR1C3 (0.52) | ALDH1A1CYP19A1AKR1C3MAPTLMNA | |
| SCHEMBL4661682 | 0.81 | CYP19A1 (0.71) | ALDH1A1CYP19A1MAPTKMT2ALMNA | |
| SCHEMBL14751071 | 0.78 | ALDH1A1 (0.71) | ALDH1A1CYP19A1AKR1C3MAPTKMT2A | |
| SCHEMBL30822628 | 0.78 | ALDH1A1 (0.71) | ALDH1A1CYP19A1AKR1C3MAPTKMT2A | |
| SCHEMBL13637461 | 0.78 | CYP19A1 (0.59) | ALDH1A1CYP19A1AKR1C3MAPTKMT2A | |
| SCHEMBL16660687 | 0.78 | ALDH1A1 (0.73) | ALDH1A1CYP19A1KMT2ALMNACYP1A2 | |
| SCHEMBL18088404 | 0.75 | ALDH1A1 (1.00) | ALDH1A1AKR1C3KMT2AKDM4EMEN1 | |
| SCHEMBL12530468 | 0.75 | KMT2A (0.59) | ALDH1A1CYP19A1KMT2ALMNAMEN1 | |
| SCHEMBL14902026 | 0.74 | KMT2A (0.62) | ALDH1A1CYP19A1MAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INCORPORATED (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MAVS, ZC3HAV1, EIF2AK2 | ALDH1A1 2676/4885CYP19A1 3957/4885AKR1C3 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.