Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4661682 | 0.85 | CYP19A1 (0.71) | CYP19A1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13637461 | 0.82 | CYP19A1 (0.59) | CYP19A1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16660687 | 0.82 | ALDH1A1 (0.73) | CYP19A1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL13637458 | 0.81 | ALDH1A1 (0.60) | CYP19A1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14049658 | 0.80 | AKR1C3 (0.59) | CYP19A1ALDH1A1CYP2C19MAPTAKR1C3 | |
| SCHEMBL13628247 | 0.79 | NAMPT (0.55) | CYP19A1ALDH1A1POLBMAPTNAMPT | |
| SCHEMBL14902026 | 0.78 | KMT2A (0.62) | CYP19A1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL2462774 | 0.77 | L3MBTL1 (0.47) | CYP19A1KMT2AALDH1A1L3MBTL1POLB | |
| SCHEMBL3564279 | 0.76 | CYP19A1 (0.67) | CYP19A1CYP1A2CYP3A4CA12ATM | |
| SCHEMBL12530468 | 0.76 | KMT2A (0.59) | CYP19A1KMT2AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MYRIAD GENETICS, INCORPORATED (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275583-A1 | ANTIVIRAL COMPOUNDS AND USE THEREOF | MAVS, ZC3HAV1, EIF2AK2 | CYP19A1 3957/4885KMT2A 4125/4885ALDH1A1 2676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.