Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855731 | 0.74 | — | — | |
| SCHEMBL12308259 | 0.69 | — | — | |
| SCHEMBL10807434 | 0.69 | — | — | |
| Metaldehyde SCHEMBL135215 | 0.69 | LMNA (1.00) | LMNA | |
| Paraldehyde SCHEMBL6032642 | 0.69 | LMNA (1.00) | LMNA | |
| Paraldehyde SCHEMBL20072682 | 0.69 | — | — | |
| Paraldehyde SCHEMBL22870 | 0.69 | — | — | |
| SCHEMBL13439771 | 0.67 | LMNA (0.39) | LMNA | |
| SCHEMBL12723015 | 0.67 | — | — | |
| SCHEMBL3440081 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120219495-A1 | NOVEL TETRAAZA MACROCYCLIC COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2012-08-30 | — | — | US | disclosed |
| EP-2476683-A2 | NOVEL TETRA-AZA MACROCYCLIC COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | Kyungpook National University Industry- Academic Cooperation Foundation (KR) | 2012-07-18 | — | — | EP | disclosed |
| US-8222177-B2 | Catalyst and reaction process | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2012-07-17 | — | — | US | disclosed |
| US-8198390-B2 | Self assembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2012-06-12 | — | — | US | disclosed |
| US-20110054190-A1 | CATALYST AND REACTION PROCESS | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-03-03 | — | — | US | disclosed |
| US-7871538-B2 | Liquid crystal composition, retardation plate, and elliptic polarizing plate | FUJIFILM CORPORATION (JP) | 2011-01-18 | — | — | US | disclosed |
| EP-2258477-A1 | CATALYST AND REACTION PROCESS | Japan Science and Technology Agency (JP) | 2010-12-08 | — | — | EP | disclosed |
| US-20100204415-A1 | SELFASSEMBLED GRAFTED POLYMERIC LAYER FOR USE IN BIOSENSOR TECHNOLOGY | IMEC (BE) | 2010-08-12 | — | — | US | disclosed |
| US-7534475-B2 | Liquid crystal compound comprising two condensed and substituted rings | FUJIFILM CORPORATION (JP) | 2009-05-19 | — | — | US | disclosed |
| US-20080186443-A1 | Liquid Crystal Composition, Retardation Plate, and Elliptic Polarizing Plate | FUJIFILM CORPORATION (JP) | 2008-08-07 | — | — | US | disclosed |
| WO-2008079427-A1 | 1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054190-A1 | CATALYST AND REACTION PROCESS | ME1, MAL2, ME2 | LMNA 4105/4885 |
| US-20120219495-A1 | NOVEL TETRAAZA MACROCYCLIC COMPOUND, PREPARATION METHOD THEREOF AND USE THEREOF | TBCA, NBAS, BMP2 | LMNA 1883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.